Ultra-high performance liquid chromatograph coupled to tandem mass spectrometer with electrospray ionization Shimadzu LCMS 8040

We offer the possibility to perform qualitative and quantitative analyses for a wide range of polar and non-polar substances using different liquid chromatography modes (reversed-phase system and hydrophilic interaction chromatography) coupled to tandem mass spectrometry. The development of analytical methods is also possible. Application of a triple quadrupole allows fragmentation of analytes enabling analysis of their structures.

Equipment:

  • Mass range: m/z2 to 2,000
  • Max scan speed: 150000 u/sec
  • Electrospray ionization source
  • Two ultra-high efficiency pressure pumps with operating pressure up to 600 bar for each one
  • Thermostatic autosampler (4 – 40°C) with injection volumes ranging from 0.1 µL to 50 µL
  • Photodiode array spectrophotometric detector collecting data in the wavelength range of 190 to 800 nm
  • Column thermostat operating in the temperature range of 4 °C to 85 °C
  • LabSolution software for data acquisition and processing

 

Advantages:

  • Simultaneous operating in positive and negative ionization mode (polarity change in 15 ms)
  • High efficiency due to the possibility of using ultra high performance liquid chromatography;
  • High speed of scanning increasing reliability of obtained results (up to 150000 measuring points per second)
  • High sensitivity and selectivity due to MRM measurement mode

 

Application area:

  • Pharmaceutical industry
  • Biochemistry
  • Medical Analytics
  • Environmental analysis
  • Medicine
  • Food Industry
  • Forensics
  • Cosmetics
  • Biosurfactants

 

Example applications:

  • Quantitative and qualitative analysis of surfactin homologs
  • Biochemical screening for genetic disorders
  • Monitoring of therapeutic activity of drugs
  • Investigation of drug metabolism
  • Determination of pesticide content in drinking water and wastewater